The question pertains to whether a nationwide metagenomic sequencing program will be sponsored or supported by the US CDC before 2025. The resolution criteria includes at least 50 total sites in at least 10 different counties actively doing metagenomic sequencing on environmental samples or random clinical samples, and one of the goals should be identification of novel pathogens. This would resolve as Yes if the program meets these conditions on or before December 31, 2024, based on credible media reports. Examples of what such a program might take include the CDC's COVID wastewater surveillance program, which already has hundreds of US counties represented and is active.